Vasco Knight@LINC 2024 | Dr. Konstantinos Stavroulakis: Cost Analysis of Target Lesion Revascularization (TLR) for Femoro-Popliteal In-Stent Restenosis (ISR)
时间: 2025-01-15
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Author: Dr. Konstantinos Stavroulakis

Institution: Associate Professor of Vascular and Endovascular Surgery, University Hospital of Munich, Germany


Summary


This presentation summarizes the COSTLY-TLR study, which analyzed the economic burden of target lesion revascularization (TLR) for femoro-popliteal in-stent restenosis (ISR) patients. Through a microeconomic analysis of 482 procedures, the study compared the costs of open surgery, hybrid surgery, and endovascular surgery. Results show that TLR costs are primarily influenced by procedure duration and equipment expenses, with open surgery being more costly than endovascular approaches.


Study Design and Key Findings


Study Design: The COSTLY-TLR study is a retrospective, multicenter microeconomic analysis involving 13 hospitals across 6 European countries, documenting the actual expenses of various TLR procedures.


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Key Findings: Open surgery costs are significantly higher than endovascular procedures due to longer surgery times and higher equipment costs. The costs of guidewires, stents, drug-coated balloons, and thrombectomy devices heavily impact total expenses.


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Cost Analysis Results


Hospitalization and Surgical Costs: The average direct surgical cost per hospitalization was €21,917, with open surgery costing the highest at €23,337. Postoperative care, including ICU stays, further increased total costs.


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Equipment Costs: Total expenses for endovascular equipment averaged around €2,979, covering guidewires, drug-coated balloons, and stents, with hybrid procedures having similar equipment costs to endovascular approaches.


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Conclusion


1. TLR for ISR incurs significant costs, with open surgery being substantially more expensive than endovascular procedures.


2. Procedure time and equipment expenses are the main cost drivers, underscoring the importance of successful initial intervention to reduce re-intervention needs.


3. Re-intervention strategies for ISR should focus on optimizing the outcomes of the initial procedure and improving follow-up protocols to decrease the rate of subsequent TLR.


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